|
KMID : 1190620080040020074
|
|
Journal of the Korean Wound Care Society
2008 Volume.4 No. 2 p.74 ~ p.83
|
|
|
Biological Mechanism to Control Skin Regeneration and Scar Formation
|
|
Yang Beom-Seok
Lee Nam-Taek
|
|
|
Abstract
|
|
|
|
Human body responds to its tissue damage by the programmed would healing process. The biological mechanism for the process is basically same for all tissue damages regardless of whether it occurs in skin or inner organs. In this process, immune cells and fibrotic cells play crucial roles with cooperative responses between them. Unfortunately this wound healing process always does not regenerate the damaged tissue as its original state. Instead the tissue repair results in the production of a fibrotic mass so called scar in many cases. We will summarize recent developments in understandings of cellular responses and biological factors to control the wound healing mechanism with focusing on skin tissue repair. We will emphasize especially why and how scar formation happens in skin wound healing. In addition we will discuss current and future therapeutic strategies for the prevention of scar formation. (J Korean Wound Management Soc 2008;4:74-83)
|
|
|
KEYWORD
|
|
|
Wound healing, Regeneration, Scar, Skin
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|